For example, here, among other genes, STAT1, IL10RA, and PTEN were underexpressed in sarcoidosis CD14 monocytes compared to controls while CXCR4, ATG12, HIF1A, CCR1, and IER3 were overexpressed, consistent with the effects of TGFB1 signaling. The gene discussed is IER3; the disease is sarcoidosis.