GNRH1 and thymoma: Moreover, in a small study pre- and post-menarchal patients treated for Hodgkin and non-Hodgkin lymphoma, thymoma, acute myeloid, and lymphoid leukemia, GnRH treatment confined a more notable benefit in preserving menstruation and fertility in postpubertal patients, whereas prepubertal girls seemed to be at less risk of COF, even in the absence of GnRH treatment (25).