HDAC9 and cancer: Lin et al., 2006 overviewed of the use of HDAC inhibitors in cancer, focusing on HDAC-mediated acetylation of histone and non-histone substrates, HDAC chemical biology, development of a new type of HDAC inhibitors, and the protein acetylation-independent effect on the activation status of signaling kinases (Seto and Yoshida, 2014).