The univariate Cox regression and Kaplan–Meier analyses indicated that nine of the regulators were associated with poor survival of the HCC cases (Figure 3A; Supplementary Figure 1), including YTHDC1, KIAA1429, HNRNPA2B1, RBM15, YTHDF2, YTHDF1, HNRNPC, METTL3, and WTAP. This evidence concerns the gene VIRMA and hepatocellular carcinoma.