Results of TIMER analysis showed that the level of KLHL5 was significantly elevated in CHOL (cholangiocarcinoma), ESCA (esophageal carcinoma), HNSC (head and neck squamous cell carcinoma), LIHC (liver hepatocellular carcinoma), LUAD (lung adenocarcinoma), LUSC (lung squamous cell carcinoma), STAD (Stomach adenocarcinoma) compared with adjacent normal samples. This evidence concerns the gene KLHL5 and carcinoma of esophagus.