KLHL5 and gastric cancer: In addition, to further analyze the correlative significance between KLHL5 expression and prognosis from published cancer microarrays, Kaplan–Meier plotter was employed and it revealed that the overexpression of KLHL5 was significantly associated with a poorer overall survival (OS) (HR 1.58, 95% CI 1.26–1.98, P = 6.8e−05) and progression-free survival (PFS) (HR 1.78, 95% CI 1.4–2.27, P = 2.2e−06) in gastric cancer patients (Figures 2I, J).