AMBRA1 interacts with Tripartite motif-containing 32 (TRIM32) (Di Rienzo et al., 2019) that is crucial as well, and indeed its deletion causes myopathy with neurological complications, both superimposable with the phenotype observed in patients with limb-girdle muscular dystrophy 2H (LGMD2H) (Saccone et al., 2008). Here, TRIM32 is linked to myopathy.