ATG5 and retinal disorder: Endothelium-specific deletion of Atg5 reduces pathological neo-vascularization in a mouse model of retinopathy (Sprott et al., 2019), and the retinal vascular hyper-sprouting phenotype induced by PKA deficiency is partially rescued by inhibition of autophagy or endothelium-specific Atg5 deletion (Zhao et al., 2019).