Additionally, it has been reported that circASPA1 promoted hepatocellular carcinoma (HCC) progression by regulating miR-326/miR-532-5p-MAPK1 signaling, and positively correlated with tumor-associated-macrophage infiltration via the miR-326/miR-532-5p-CSF-1 axis (Hu et al., 2019). The gene discussed is MAPK1; the disease is neoplasm.