TMPRSS2 and posterior cortical atrophy: Among the 14 biomarkers, we found that mRNA expression of CST3, VEGFA, GOLM1, CCND1, LMTK2, PMP22, and TMPRSS2 was significantly upregulated in urine samples from higher-risk PCa patients compared with that of lower-risk group (Figures 2A–G).