TMPRSS2 and posterior cortical atrophy: The mean value of relative mRNA expression CtS of these genes all increased significantly in higher-risk PCa compared to lower-risk PCa [CST3 was increased by 1,008 (p < 0.0001), VEGFA was increased by 953 (p < 0.0001), GOLM1 was increased by 813 (p = 0.000), CCND1 was increased by 727 (p = 0.002), LMTK2 was increased by 552 (p = 0.006), PMP22 was increased by 534 (p = 0.007), and TMPRSS2 was increased by 523 (p = 0.007)].