BCL11B and acute lymphoblastic leukemia: Chromosomal rearrangements, such as translocation and deletions leading to the loss of function of Bcl11b, were reported in 10% of studied T-ALL cases (Nagel et al., 2003; Przybylski et al., 2005; Van Vlierberghe et al., 2008; Gutierrez et al., 2011).