The NLR family pyrin domain containing 3 (NLRP3) inflammasome sensor has been proven central to age related and viral-induced inflammation in humans and other mammals.NLRP3 is vital to the inflammasome of cells and its role is to recognize cellular stresses such as mitochondrial damage or oxidative stress, in addition to bacterial or viral infections. The gene discussed is NLRP3; the disease is viral infectious disease.