Our Kaplan-Meier analysis of public–accessible CRC microarray databases (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE39582), show that low KCNQ1 and KCNE3 expression are associated with poor relapse-free survival in patients with CRC and high expression of these Kv channel subunits correlate with better survival only in the female (Figure 8). The gene discussed is KCNE3; the disease is colorectal carcinoma.