In recent years, an increasing number of serum markers, which can be conveniently gained, were regarded as prognostic markers for NPC patients, containing Epstein–Barr virus DNA (EBV-DNA) (10), hemoglobin (HGB) (11), albumin (ALB) (12), C-reactive protein (CRP) (13), lactate dehydrogenase (LDH) (14) and so on. This evidence concerns the gene ALB and nasopharyngeal carcinoma.