Considering that WTAP did not carry a consistent gene abnormal expression trend in Oncomine database (Figures 1A and S1), and that METTL3 and RBM15B were only downregulated in Oncomine database but not in TCGA breast cancer samples (Figures 1A and S2), we excluded these three genes and only included METL14 and ZC3H13 for subsequent studies (Figure 2). The gene discussed is WTAP; the disease is breast cancer.