For example, Zhao et al. (2017) demonstrated that lncRNA TUG1 could competitively sponge miR-382, thereby regulating EZH2. Their experiments further revealed that TUG1 overexpression promoted cellular proliferation and migration, and contributed to epithelial-mesenchymal transition (EMT) formation in PC cell lines (Zhao et al., 2017). The gene discussed is EZH2; the disease is pachyonychia congenita.