In GSE70905, YTHDC1 (p < 0.05), IGFBP1 (p < 0.001), ALKBH5 (p < 0.001), WTAP (p < 0.001), YTHDF3 (p < 0.001) and HNRNPA2B1 (p < 0.001) were down-regulated in breast cancer to the adjacent. The gene discussed is IGFBP1; the disease is breast carcinoma.