Intriguingly, the mRNA expressions of ACOT1/2/11/13 seemed not to be significantly associated with the increase in TNM stages, whereas patients who were in more advanced TNM stages had a tendency to express higher ACOT8. Next, we analyzed ACOTs expressions in distinct histological grades of ccRCC (Figures 4F–J). This evidence concerns the gene ACOT1 and nonpapillary renal cell carcinoma.