We excluded the first two possibilities because of the absence of candidate variants in the target genes analyzed, including those underlying pigmentation disorders with platelet storage pool defects, such as Hermansky–Pudlak syndrome and non-syndromic oculocutaneous albinism (OCA) with platelet dysfunction (caused by biallelic mutations in TYR and TYRP). This evidence concerns the gene TYR and oculocutaneous albinism.