We focused on Epithelium-dominant TFs and found those encompassed by BEC-SEs (Supplementary Figure S1F) have been previously implicated in lung development (FOXA1) (Besnard et al., 2005) and asthma, nasal polyposis, and mucociliary development (TP63, TP73) (Hackett et al., 2009; Li et al., 2009; Warner et al., 2013; Nemajerova et al., 2016). This evidence concerns the gene TP63 and asthma.