NoF1 subgroup had lower age-related risks of PCT (p = 0.033) and CHB (p = 0.006) compared with NoF2, but risks of RA (p = 0.717), RCC (p = 0.171), and PHEO (p = 0.711) were similar between the two subgroups (Figure 2). This evidence concerns the gene MRPL49 and renal cell carcinoma.