The results obtained using GSE53625 and TCGA_HNSCC show that higher expression of SPP1 and BGN was related to worse overall survival in ESCC (Figures 5A–D) as was higher expression of three differentially expressed lncRNAs (LINC01614, LINC01415, and NKILA) (Figures 5E–G). The gene discussed is SPP1; the disease is esophageal squamous cell carcinoma.