However, in recent years, the ability of mast cells and basophils to exert adjuvant functions in immune sensitization to allergens and of IgG antibodies to block IgE-mediated food allergy has been recognized and the role of the inhibitory IgG receptor, FcγRIIb, in potently inhibiting food allergies has really come into focus. The gene discussed is FCGR2B; the disease is food allergy.