PSMB8 and COVID-19: Furthermore, 11 genes (STAT1, STAT2, JAK2, PSMB8, TAP1, IFI35, IFIT1, IFITM1, IFIT3, OAS1, and MX1) were up-regulated in the “human immune response to tuberculosis” pathways in the high viral load compared to the low viral load COVID-19 samples (Table 4 and Figure S8A).