CD4 and rheumatoid arthritis: Proportions of Th17 (CD4+CCR6+CXCR3-) cells were significantly higher in RA (19, 1%; 11, 4–24%) and OA (17, 9%; 10; 2–25, 7%) in comparison to HCs (10, 3%; 3, 9–20, 5%) (Figure 1C).