In this study, because of the high conservation of miR-134 between human and mouse, mouse pituitary αT3-1 cells were used to determine the effect of SDF-1α on miR-134 expression in vitro model, and detect the regulation of miR-134 on VEGFA synthesis, proliferation, migration, and invasion in tumor cells treated with SDF-1α. The gene discussed is VEGFA; the disease is neoplasm.