The results of this study indicated that (1) serum levels of IL-6 and IL-8 were increased in MAP patients; (2) IL-2R levels had a negative correlation with the intensity of positive psychotic symptoms, but IL-6 and IL-8 levels did not; (3) cognitive dysfunction was present in the MAP patients (MOCA total scores of 26 and higher are generally considered normal); and (4) the severity of different types of cognitive impairment was positively correlated with IL-6, IL-8, and IL-10 levels. Here, IL6 is linked to Cognitive impairment.