ALOX5 and Seizure: Other identified ferroptosis targets including SLC7A11 (ANOVA, F (5,24) = 10.68, p < 0.001), 5-LOX (ANOVA, F (5,24) = 23.53, p < 0.001) and ACSL4 (ANOVA, F (5,24) = 4.521, p = 0.008) were slightly or hardly affected in KA-induced epileptic seizures when treatment with lapatinib (Figures 7A,C–E).