The prevalence of ATTR V30M amyloidosis is estimated to be 0.87–1.1 per 1 000 000 individuals (Adams et al., 2014) and the disease has been considered endemic in the north of Portugal (Sousa et al., 1995), Japan (Kato-Motozaki et al., 2008), and Sweden (Sousa et al., 1993). The gene discussed is TTR; the disease is amyloidosis.