The putative upregulation of the oxidative phosphorylation pathway in PD is mostly driven by NADH dehydrogenase genes such as NDUFS8, NDUFS7, and NDUFA11, which take part in mitochondria’s complex I, already reported to be impaired in PD (Keeney, 2006). The gene discussed is NDUFA11; the disease is Parkinson disease.