PHCC (0.65±0.2) and HCC (0.63±0.2) showed higher p-ULK1(Ser757)/ULK1 protein levels compared to M (0.30±0.2; q = 0.02 and q = 0.003 respectively) (Fig 4E). The gene discussed is ULK1; the disease is hepatocellular carcinoma.