Surprisingly, a remarkable induction of OATP1B1 and OATP1B3 was detected in Ad-HNF3γ-infected HCC cells (Fig. 7c), and a ChIP assay revealed the direct interaction of HNF3γ with the OATP1B1 and OATP1B3 promoter (Fig. 7d). The gene discussed is SLCO1B3; the disease is hepatocellular carcinoma.