ALKBH5 and hepatocellular carcinoma: Interestingly, we found that inhibition of m6A methyltransferase such as METTL3, METTL14, or WTAP remarkably decreased the expression of HNF3γ, and knockdown of the m6A demethylase FTO but not ALKBH5 significantly increased the expression of HNF3γ (Supplementary Fig. S3d, e), suggesting that m6A modification could be involved in the HNF3γ reduction in HCC cells.