2014; Potter et al. 2016). Sirtuin 6 (SIRT6) protein is a chromatin binding factor that was initially described as an inhibitor of gene instability (Mostoslavsky et al. 2006). During energy metabolism, SIRT6 regulates the fat and glucose metabolism, which is a key regulator of energy stress and is closely related to the process of tumour growth (Sebastián and Mostoslavsky 2015). With the metabolic profile used for energy production is elucidated, regulating tumour metabolism is a new therapeutic strategy to inhibit tumour growth (Zhang and Yang 2013). The gene discussed is SIRT6; the disease is neoplasm.