GnRHR‐AAb, GnRHR‐activating autoantibodies; LH, luteinizing hormone; IR, insulin resistance; TNF‐α, tumor necrosis factor‐alpha; IL‐1α, interleukin −1 alpha; IL‐4, interleukin 4; IL‐10, interleukin 10; IL‐18, interleukin 18. The gene discussed is IL4; the disease is Insulin resistance.