All these findings give a shred of growing evidence that AD is related to apoptosis either through the accumulation of Ab, which can induce neuronal apoptosis or by oxidative stress, which causes a cytochrome c release and activates caspase‐9 and caspase‐3 and overproduction of free radicals (Xing et al., 2018). Here, CYCS is linked to Alzheimer disease.