2016). ALT is regarded as the ‘gold standard’ for the clinical biochemical detection of liver injury due to its sensitivity, and 1% of hepatocyte necrosis can double the ALT level (Heydrnejad et al. 2015). AST mainly exists in the mitochondria of hepatocytes and is released into the blood when mitochondria disintegrate due to injury and rupture of hepatocytes (Ennulat et al. 2010). ALP is one of the main markers of hepatobiliary function and cholestasis; in addition, an elevated ALP level indicates adverse effects of drugs on liver function (Ma et al. 2018). Here, GPT is linked to cholestasis.