H3-4 and pituitary gland adenoma: Hsa-miR-184 was found upregulated in GH-producing pituitary tumors compared with normal pituitary [22], while hsa-miR-185-5p is overexpressed in GHomas not responding to SSTR treatment, and its high expression corresponds to high proliferation and inhibits the apoptosis of GH3 pituitary adenoma cells [30].