In this respect, the group of Joke den Haan and Yvette van Kooyk (both University of Amsterdam, Amsterdam, the Netherlands) proposes the development of virus-like liposomes as a novel dendritic cell-targeted vaccination strategy in which they will use ligands of CD169 molecules expressed on antigen presenting cells, immune-activating viral-mimic molecules as adjuvant, and encapsulated tumor antigens [97,98]. Here, SIGLEC1 is linked to neoplasm.