Validation and establishment of reference levels for novel biomarkers such as CysC, NGAL, and KIM-1, some of which are potentially important in the diagnosis of prerenal dysfunction [89], and other lesser-known biomarkers such as insulin-like growth factor binding protein (IGFBP) that could possibly predict renal recovery [90], would be useful in demonstrating the AKI-CKD continuum in agricultural workers. Here, LCN2 is linked to acute kidney injury.