In PCa, luciferase reporter assay demonstrated that both miR-17-5p/3p targeted the 3’-UTR of TIMP metallopeptidase inhibitor 3 (TIMP3), and ectopic expression of pre-miR-17 promoted tumor growth and invasion, which was mediated by TIMP3 repression [72]. The gene discussed is TIMP3; the disease is posterior cortical atrophy.