More recently, studies examining the role of RIPK1 in a viral hepatitis model using murine hepatitis virus type 3 (MHV3) have found that parenchymal cell deficiency of RIPK1, RIPK1LPC-KO, sensitizes mice to apoptosis from MHV3 and PAMPs such as poly I:C. This evidence concerns the gene RIPK1 and animal viral hepatitis.