MAP3K5 and metabolic dysfunction-associated steatohepatitis: Wang et al. report that cFlip can directly interrupt the activation of the mitogen-activated protein kinase (MAPK) apoptosis signal-regulating kinase 1 (ASK1) dimerization, thus inhibiting NASH by blocking ASK1 to cJun-N-terminal Kinase (JNK) signaling [115].