KDR and neoplasm: The data showed a tendency between the heterosis genetic model of KDR rs1870377 and time to tumour progression, having the homozygous A and T increased risk to disease progression (HR = 1.4, 95% CI (1.0–2.0), p = 0.054) and to death (HR = 1.7, 95% CI (1.0–2.7), p = 0.034).