Genes associated with ECM remodelling (e.g., Tgf-β3 and Mmp) and inflammation (e.g., Tlr 4 and Tlr 13) related to Colorectal Cancer Metastasis Signalling were predicted to be active in DEB1 when compared to DEB2 (Figure 2I; Data S2). The gene discussed is TGFB3; the disease is colorectal cancer.