Finally, they investigated whether CXCL4 regulates the recruitment of MDSCs into tumor tissue and found that CXCL4 overexpression decreased MDSC migration in vitro, and flow cytometry analysis revealed that CD11b+/Gr1+ MDSC cells were upregulated in the tumor tissues and peritoneal cavity after laparotomy. The gene discussed is ITGAM; the disease is neoplasm.