STING1 and infection: Infection by different viruses has been reported to trigger IFI16 translocation to the cytosol [57,58] and to cooperate with the cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) synthase (cGAS) to enhance the stimulator of interferon gene (STING)-mediated activation of IFN expression [51,59,60].