AURKA and cancer: AURKA overexpression enhances cell survival by suppressing autophagy through activating the mammalian target of rapamycin (mTOR) signaling [21,23,24], activating anti-apoptosis signaling, and/or cancer cell survival and chemoresistance by activating of PI3K/Akt/GSK3 [25,26] and NF-κB signaling cascades [27,28].