We also observed a significant increase in the percentage of tumor macrophages in the tumors with the drug treatment (1.5-fold, p = 0.03), suggesting potential recruitment of phagocytic cells to reduce tumor burden, Figure 2C. Lastly, regarding blood monocytes, the drug treatment resulted in less inflammatory monocytes (i-mono) with PDL1 stain by mean fluorescence intensity (MFI) only (p = 0.01 vs. vehicle), Figure 2E. Here, CD274 is linked to neoplasm.