CPT1A and posterior cortical atrophy: Additionally, analysis of the production of long-chain acyl carnitines (the product of CPT1 activity) was also significantly decreased in the TRAMPC1 cells treated with 75 μM ranolazine for 48 h (20% less, p = 0.033), Figure 5B. Parallel results were also observed in MyC-CaP mouse PCa cells (40% less, p = 0.028), which is another model of aggressive PCa that is androgen-independent, Figure 5C.