Patients with zero unfavorable alleles (IL-8-251 AT/TT and VEGF +936 CC allele) had lower risk of tumor recurrence than patients with one unfavorable allele (RR 1.853 (1.045–3.284)) or two unfavorable genes (RR 4.910 (1.047–23.031), adjusted p-value 0.034) (Table 5, Figure 1c). Here, CXCL8 is linked to neoplasm.