Polymorphic variants of Aldehyde dehydrogenase 2 (ALDH2) were found to be associated with alcoholic cardiomyopathy and stroke [69], and hypertensive male carriers of rs671 in the ALDH2*1/*1 genotype were more likely to have CMBs than ALDH2 *2 allele carriers (Table 4) [70]. The gene discussed is ALDH2; the disease is Stroke.