The crucial role of PCDH10 in synaptic connectivity and circuit formation has been also confirmed during investigations performed on PCDH10-heterozygous mice (PCDH10+/−) where it has been demonstrated that even a partial reduction in functional PCDH10 causes biological alterations at amygdala level that are associated with neurodevelopmental disorders [60]. The gene discussed is PCDH10; the disease is neurodevelopmental disorder.