Dose–response curves comparing two isogenic ovarian cancer cell lines, UWB1.289-BRCA1 mutated and UWB1.289-BRCA1 restored, show a leftward shift in the dose–response curve for UWB1.289 (radiation dose for 50% survival (D50) 2.31 ± 0.21 Gy) compared to UWB1.289-BRCA1 restored (3.45 ± 0.36 Gy) (Figure 3A). This evidence concerns the gene BRCA1 and ovarian cancer.