CASP3 and infection: Results showed that Z-VAD inhibited DENV-induced caspase-3 cleavage (Figure 3A) and cell death rates (48 h post-infection: 50.50 ± 2.88% versus 35.37 ± 1.78%, about 0.70-fold change, p < 0.001; 72 h post-infection: 76.50 ± 0.40% versus 68.73 ± 3.38%, about 0.90-fold change, p < 0.001) (Figure 3B).