Interestingly, although there is no change of Beclin-1 expression from 12 to 24 h post-infection, a decrease in the full length of Beclin-1 (around 60 kDa) and an increase in cleavage forms (around 50 and 40 kDa) were notable at 48 h post-infection. The gene discussed is BECN1; the disease is infection.